Rat Leucine-Rich Repeat-Containing Protein 15 (LRRC15) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits LRRC15
proveedor
Abbexareference
abx531348Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Leucine-Rich Repeat-Containing Protein 15 (LRRC15) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Leucine-rich repeat-containing protein 15 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LRRC15 is a collagen-binding protein with a significant role in regulating extracellular matrix (ECM) remodeling and cell-matrix interactions it is widely expressed in stromal cells and tumor-associated fibroblasts where it participates in modulating cell adhesion and migration particularly in cancer and wound healing contexts LRRC15 has been identified as a critical component of the tumor microenvironment facilitating tumor progression and metastasis by influencing ECM organization and stiffness it is also involved in immune modulation through its interactions with immune cell receptors recent studies indicate its expression is upregulated in fibrotic diseases such as idiopathic pulmonary fibrosis (IPF) and systemic sclerosis implicating it in pathological ECM deposition and remodeling LRRC15's potential as a therapeutic target is being explored particularly in oncology where its expression correlates with resistance to immune checkpoint inhibitors and poor prognosis in several cancers ongoing research aims to clarify its regulatory mechanisms in ECM biology and its cross-talk with other signaling pathways driving tissue repair and fibrosis
Características del producto
category
ELISA Kits
immunogen target
Leucine-Rich Repeat-Containing Protein 15 (LRRC15)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
LIBLeucine-rich repeat protein induced by beta-amyloid homolog ,hLib
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
LRRC15
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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