Rat Leucine-Rich Repeat-Containing Protein 15 (LRRC15) ELISA Kit

Este producto es parte de LRRC - Leucine-rich repeat-containing protein
Rat Leucine-Rich Repeat-Containing Protein 15 (LRRC15) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits LRRC15

proveedor

Abbexa

reference

abx531348

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Leucine-Rich Repeat-Containing Protein 15 (LRRC15) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Leucine-rich repeat-containing protein 15 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

LRRC15 is a collagen-binding protein with a significant role in regulating extracellular matrix (ECM) remodeling and cell-matrix interactions it is widely expressed in stromal cells and tumor-associated fibroblasts where it participates in modulating cell adhesion and migration particularly in cancer and wound healing contexts LRRC15 has been identified as a critical component of the tumor microenvironment facilitating tumor progression and metastasis by influencing ECM organization and stiffness it is also involved in immune modulation through its interactions with immune cell receptors recent studies indicate its expression is upregulated in fibrotic diseases such as idiopathic pulmonary fibrosis (IPF) and systemic sclerosis implicating it in pathological ECM deposition and remodeling LRRC15's potential as a therapeutic target is being explored particularly in oncology where its expression correlates with resistance to immune checkpoint inhibitors and poor prognosis in several cancers ongoing research aims to clarify its regulatory mechanisms in ECM biology and its cross-talk with other signaling pathways driving tissue repair and fibrosis

Características del producto

category

ELISA Kits


immunogen target

Leucine-Rich Repeat-Containing Protein 15 (LRRC15)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

LIBLeucine-rich repeat protein induced by beta-amyloid homolog ,hLib


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

LRRC15


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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