Rat Leptin (LEP) CLIA Kit
845€ (96 tests)
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935106861
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name
Rat Leptin (LEP) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx190613
tested applications
CLIA
Description
Rat Leptin (LEP) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Leptin (LEP) |
| Reactivity | Rat |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 27.4 pg/ml - 20000 pg/ml |
| Sensitivity | < 12.2 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | OB,OBS,LEPD,Obese protein,Obesity factor |
| Background | CLIA Kits LEP |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Leptin ( LEP) is an adipokine predominantly produced by adipocytes that plays a key role in regulating energy balance, appetite, and metabolism by acting on the hypothalamus Leptin signals through its receptor (LEPR) to suppress food intake and promote energy expenditure, maintaining body weight homeostasis Circulating leptin levels are proportional to fat mass, with increased levels observed in obesity due to leptin resistance Dysregulation of leptin signaling is associated with metabolic syndrome, type 2 diabetes, and cardiovascular diseases Leptin also exerts immunomodulatory functions, influencing the activity of T cells, macrophages, and other immune cells to enhance pro-inflammatory responses It is implicated in autoimmune diseases, including rheumatoid arthritis and lupus, where elevated leptin promotes chronic inflammation Leptin’s role extends to bone metabolism, reproductive function, and wound healing, highlighting its pleiotropic effects in energy homeostasis and systemic physiology
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