Rat Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for SLC7A5
proveedor
Abbexareference
abx530724Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
SLC7A5, also known as LAT1 (L-type amino acid transporter 1), is a transmembrane protein crucial for amino acid transport across the plasma membrane. It is part of the solute carrier family 7 (SLC7), specifically associated with the transport of large neutral amino acids (LNAAs) like leucine, isoleucine, valine, phenylalanine, and tryptophan, which are essential for various cellular functions. LAT1 is a high-affinity, sodium-independent transporter and functions as part of a heteromeric complex with SLC3A2 (4F2hc or CD98), which acts as a chaperone protein for the proper membrane localization and functionality of LAT1. SLC7A5 plays a significant role in cellular growth and proliferation, and it is highly expressed in rapidly dividing cells. It is abundant in tissues with high metabolic demands, such as the brain, placenta, and certain immune cells, as well as in many cancer cell types, where it facilitates the increased amino acid demand required for protein synthesis and tumor growth. LAT1 is also integral to the blood-brain barrier, as it enables the transport of essential amino acids into the brain, thereby impacting neurotransmitter synthesis.
Características del producto
category
ELISA Kits
immunogen target
Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Large neutral amino acids transporter small subunit 1,4F2 light chain,E16,CD98,LAT1,4F2LC,MPE16,D16S469E,CD98 light chain,Integral membrane protein E16
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
SLC7A5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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