Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) Antibody

Este producto es parte de SLC7A5 - solute carrier family 7 member 5
Product Graph
637€ (100 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx115717
tested applications
ELISA

Description

Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) Antibody is a Rabbit Polyclonal Antibody against Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA
Buffer
PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q01650
Gene ID
8140
OMIM
600182
Alias
Large neutral amino acids transporter small subunit 1,4F2 light chain,E16,CD98,LAT1,4F2LC,MPE16,D16S469E,CD98 light chain,Integral membrane protein E16
Background
Antibody anti-SLC7A5
Status
RUO

Descripción

SLC7A5, also known as LAT1 (L-type amino acid transporter 1), is a transmembrane protein crucial for amino acid transport across the plasma membrane. It is part of the solute carrier family 7 (SLC7), specifically associated with the transport of large neutral amino acids (LNAAs) like leucine, isoleucine, valine, phenylalanine, and tryptophan, which are essential for various cellular functions. LAT1 is a high-affinity, sodium-independent transporter and functions as part of a heteromeric complex with SLC3A2 (4F2hc or CD98), which acts as a chaperone protein for the proper membrane localization and functionality of LAT1. SLC7A5 plays a significant role in cellular growth and proliferation, and it is highly expressed in rapidly dividing cells. It is abundant in tissues with high metabolic demands, such as the brain, placenta, and certain immune cells, as well as in many cancer cell types, where it facilitates the increased amino acid demand required for protein synthesis and tumor growth. LAT1 is also integral to the blood-brain barrier, as it enables the transport of essential amino acids into the brain, thereby impacting neurotransmitter synthesis.

Related Products

FNab11016

SLC7A5 antibody

Ver Producto
abx007200

Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) Antibody

Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) Antibody is a Rabbit Polyclonal Antibody against Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5).

Ver Producto
abx037465

Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) Antibody

Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5) Antibody is a Rabbit Polyclonal Antibody against Large Neutral Amino Acid Transporter 1 / LAT1 (SLC7A5).

Ver Producto