Rat Interleukin 7 (IL7) Protein

Este producto es parte de IL7 - interleukin 7
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208€ (10 µg)

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935106861
info@markelab.com
name
Rat Interleukin 7 (IL7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654058
tested applications
WB, SDS-PAGE

Description

Rat Interleukin 7 (IL7) protein is a recombinant protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interleukin 7 (IL7)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: His29-Asn152
Tag: N-terminal His tag
Origin
Rat
Conjugation
Unconjugated
Observed MW
Calculated MW: 18.1 kDa  Observed MW: 18 kDa
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
P56478
Alias
IL-7
Background
Protein IL7
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Endotoxin Level: < 1.0 EU per 1 µg (determined by the LAL method)
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

Interleukin-7 (IL7) is a critical cytokine primarily involved in the development, survival, and homeostasis of immune cells, particularly T cells and B cells. It plays an essential role in lymphopoiesis, ensuring the proper function and maintenance of the adaptive immune system. IL-7 is produced mainly by stromal cells in the bone marrow and thymus, but it is also secreted by epithelial cells in other tissues, such as the intestines, liver, and skin. Unlike many cytokines, IL-7 is not produced by immune cells themselves but acts as a growth factor necessary for immune cell survival and proliferation. IL-7 is vital for the survival of naïve and memory T cells, supporting the homeostasis of these populations throughout life. It also supports the early stages of B cell development in the bone marrow and ensures the development of a healthy and functional immune system. IL-7’s function in maintaining T cell homeostasis and supporting immune recovery has made it a target of interest in immunotherapy, particularly for treating immune deficiencies, enhancing cancer immunotherapy, and facilitating immune reconstitution in HIV patients.

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