Rat Interleukin 6 Receptor (IL6R) ELISA Kit
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935106861
info@markelab.com
Precio
525€ (96 tests)
Elisa Kits IL6R
proveedor
Abbexareference
abx255770Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Interleukin 6 Receptor (IL6R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Interleukin 6 Receptor (IL6R) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
IL6R is a key component of the interleukin-6 (IL6) signaling pathway, consisting of a membrane-bound and soluble form (sIL6R), which binds IL6 and mediates downstream effects via the gp130 co-receptor This interaction activates the JAK/STAT3, MAPK, and PI3K/AKT pathways, regulating immune responses, inflammation, and hematopoiesis IL6R signaling is critical in acute-phase responses, B cell maturation, and T cell proliferation Dysregulation of IL6R activity is implicated in chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease, and systemic lupus erythematosus (SLE) In cancer, IL6R signaling supports tumor progression, angiogenesis, and immune evasion Therapeutic targeting of IL6R, such as with tocilizumab, is effective in reducing inflammation and cytokine storm in conditions like COVID-19, autoimmune disorders, and hematological malignancies
Características del producto
category
ELISA Kits
immunogen target
Interleukin 6 Receptor (IL6R)
reactivity
Rat
test range
78 pg/ml - 5000 pg/ml
sensitivity
46.9 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
IL6Q,gp80,CD126,HIES5,IL-6R,IL6RA,IL6RQ,IL-1Ra,IL-6RA,IL6QTL,IL-6R-1,L-6R-Alpha,IL-6Rα
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
IL6R
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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