Rat Interferon Alpha 4 (IFNa4) Protein
234€ (10 µg)
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name
Rat Interferon Alpha 4 (IFNa4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067333
tested applications
WB, SDS-PAGE
Description
Recombinant Interferon Alpha 4 (IFNa4) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interferon Alpha 4 (IFNa4) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 21.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg33-Lys189 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | D3ZFH0 |
| Alias | INFA4,IFN-alpha4a,IFN-alpha-4,Interferon alpha-4B,Interferon alpha-76,Interferon alpha-M1 |
| Background | Protein IFNA4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interferon Alpha 4 (IFNA4) is another member of the type I interferon family that contributes to the antiviral immune response. While less characterized than IFNA1 and IFNA2, IFNA4 exhibits similar functional properties, including activation of the IFNAR pathway and induction of interferon-stimulated genes that inhibit viral replication and modulate the immune response. Studies suggest that IFNA4 may have unique regulatory functions or tissue-specific roles within the broader interferon response. Its expression and functional significance may vary depending on the type of infection or immune challenge. As with other type I interferons, IFNA4's dysregulation could contribute to autoimmune conditions, and understanding its precise role in health and disease remains an area of ongoing research.
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