Interferon Alpha 4 (IFNA4) Antibody
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Pida mas información
935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-IFNA4
proveedor
Abbexareference
abx034855Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Background
Interferon Alpha 4 (IFNA4) is another member of the type I interferon family that contributes to the antiviral immune response. While less characterized than IFNA1 and IFNA2, IFNA4 exhibits similar functional properties, including activation of the IFNAR pathway and induction of interferon-stimulated genes that inhibit viral replication and modulate the immune response. Studies suggest that IFNA4 may have unique regulatory functions or tissue-specific roles within the broader interferon response. Its expression and functional significance may vary depending on the type of infection or immune challenge. As with other type I interferons, IFNA4's dysregulation could contribute to autoimmune conditions, and understanding its precise role in health and disease remains an area of ongoing research.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Interferon Alpha 4 (IFNA4)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Purified through a protein A column, followed by peptide affinity purification.
recommended dilution
WB: 1/1000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IFNA4
dry ice
No
availability
Shipped within 5-10 working days.
alias
INFA4,IFN-alpha4a,IFN-alpha-4,Interferon alpha-4B,Interferon alpha-76,Interferon alpha-M1
uniprot id
NCBI accession
NP_066546.1
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