Rat Intercellular Adhesion Molecule 1 (ICAM1) Protein
312€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Intercellular Adhesion Molecule 1 (ICAM1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694330
tested applications
SDS-PAGE
Description
Rat Intercellular Adhesion Molecule 1 (ICAM1) Protein is a recombinant Rat protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: Calculated MW: 89.12 kDa Observed MW (SDS-PAGE): 90 kDa Sequence Fragment: Met1-Thr493 Tag: C-terminal hFc tag |
| Expression | Recombinant |
| Purity | >95% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute in sterile H2O. Do not vortex. |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store lyophilized between -20 °C and -80 °C. |
| Dry Ice | No |
| UniProt ID | Q00238 |
| Gene ID | 25464 |
| Alias | BB2,CD54,P3.58,ICAM-1 |
| Background | Protein ICAM1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Intercellular Adhesion Molecule 1 (ICAM-1) is a protein encoded by the ICAM1 gene in humans. It plays a crucial role in the immune response by aiding in the adhesion of leukocytes to the endothelial cells lining blood vessels. ICAM-1. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium. ICAM-1 is a transmembrane protein possessing an amino-terminus extracellular domain, a single transmembrane domain, and a carboxy-terminus cytoplasmic domain. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the protein. ICAM-1 is important for the process of leukocyte extravasation, which is how white blood cells move from the bloodstream to infected or injured tissues. It helps leukocytes stick to endothelial cells, a crucial step in the inflammatory response. ICAM-1 can also trigger intracellular signaling events when it binds to its ligands, influencing cellular processes related to inflammation and immune responses.
Related Products
Canine ICAM-1(Intercellular Adhesion Molecule 1) ELISA Kit
Ver Producto
Human sICAM-1/CD54(Soluble Intercellular Adhesion Molecule 1) ELISA Kit
Ver Producto