Rat Immunoglobulin Superfamily, Member 2 (IGSF2) Protein

Este producto es parte de IGSF - immunoglobulin superfamily member
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247€ (10 µg)

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935106861
info@markelab.com
name
Rat Immunoglobulin Superfamily, Member 2 (IGSF2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167745
tested applications
WB, SDS-PAGE

Description

Immunoglobulin Superfamily, Member 2 Protein is a recombinant Rat protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetImmunoglobulin Superfamily, Member 2 (IGSF2)
HostE. coli
OriginRat
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 60.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr666-Arg937 Tag: N-terminal His tag and GST tag
ExpressionRecombinant
Purity> 90%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-7 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
AliasV7,IGSF2,EWI-101,Glu-Trp-Ile EWI motif-containing protein 101,Cell surface glycoprotein V7
BackgroundProtein IGSF2
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

IGSF2, also known as CD101, is a glycoprotein expressed on immune cells, including T cells, dendritic cells, and monocytes. It plays a role in regulating immune responses, particularly in modulating T cell activation and promoting immune tolerance. Structurally, IGSF2 contains multiple Ig-like domains, which enable interactions with other immune cell receptors and ligands. IGSF2 has been implicated in inflammatory diseases such as inflammatory bowel disease (IBD), where its dysregulation may contribute to immune hyperactivation. It is also being studied for its role in tumor immunity and autoimmune disease susceptibility.

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