Rat Iapp(Islet amyloid polypeptide) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Iapp(Islet amyloid polypeptide) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0374
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Competitive ELISA, Coated with Antigen |
| Test Range | 78.125-5000pg/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | P12969 |
| Alias | Amylin,IAP,Diabetes-Associated Peptide Diabetes-Associated Peptide |
| Background | Elisa Kits IAPP |
| Status | RUO |
Islet amyloid polypeptide (IAPP), also known as amylin, is a 37-residue peptide hormone produced by the pancreatic beta cells. IAPP plays a role in regulating glucose metabolism, primarily by slowing gastric emptying and reducing glucagon secretion. in conditions such as type 2 diabetes mellitus, IAPP can misfold and aggregate, forming amyloid fibrils. These amyloid fibrils can accumulate in the pancreas, particularly in the islets of Langerhans. This aggregation of amyloid fibrils is associated with beta cell dysfunction, apoptosis , and progression of type 2 diabetes. Amyloid deposits originating from islet amyloid polypeptide (IAPP), are frequently observed in the pancreatic islets of individuals with type 2 diabetes mellitus or those afflicted with insulinoma cancer. Although the connection between amylin and the onset of type 2 diabetes has been recognized for some time, pinpointing its direct causative role has proved challenging. Some research indicates that amylin, and beta-amyloid (Abeta) linked to Alzheimer's disease, could trigger apoptotic cell death in insulin-producing beta cells. This effect may have implications for the progression of type 2 diabetes.
Related Products
Islet Amyloid Polypeptide (IAPP) Antibody
Islet Amyloid Polypeptide Antibody is a Mouse Monoclonal against Islet Amyloid Polypeptide.
Ver Producto
Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit
Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Islet Amyloid Polypeptide (IAPP) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Islet Amyloid Polypeptide (IAPP)
Ver Producto
Human Islet Amyloid Polypeptide (IAPP) CLIA Kit
Human Islet Amyloid Polypeptide (IAPP) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Islet Amyloid Polypeptide (IAPP).
Ver Producto