Rat Hepatocyte Growth Factor (HGF) Protein
273€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Hepatocyte Growth Factor (HGF) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067070
tested applications
WB, SDS-PAGE
Description
Recombinant Hepatocyte Growth Factor (HGF) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Hepatocyte Growth Factor (HGF) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 20.4 kDa Observed MW (SDS-PAGE): 20 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Cys306-Glu471 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P17945 |
| Alias | SF,HGFB,HPTA,F-TCF,DFNB39,Fibroblast-Derived Tumor Cytotoxic Factor |
| Background | Protein HGF |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Hepatocyte Growth Factor (HGF), also known as scatter factor, is a multifunctional cytokine primarily secreted by mesenchymal cells. It plays a pivotal role in various physiological and pathological processes, including cell proliferation, migration, morphogenesis, and angiogenesis. HGF exerts its biological effects through binding to its receptor, c-MET, a tyrosine kinase receptor highly expressed on epithelial cells, endothelial cells, and other cell types. This ligand-receptor interaction activates numerous signaling pathways, such as PI3K/AKT and MAPK, promoting tissue regeneration and wound healing. HGF is critically involved in liver regeneration and repair mechanisms, hence its name, but it also has significant implications in tumor progression and metastasis in cancers where c-MET is overexpressed or dysregulated. Clinically, HGF and its receptor c-MET are being explored as therapeutic targets for cancer treatments, given their role in oncogenesis and tumor angiogenesis. Elevated HGF levels in plasma have also been investigated as potential biomarkers for various diseases, including liver dysfunction and cancers.
Related Products
Human HGF (Hepatocyte Growth Factor) ELISA Kit
Ver Producto
Porcine HGF (Hepatocyte Growth Factor) ELISA Kit
Ver Producto