Rat Glycoprotein 5 (GP5) ELISA Kit
611€ (96 tests)
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name
Rat Glycoprotein 5 (GP5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx353704
tested applications
ELISA
Description
Rat Glycoprotein 5 (GP5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Glycoprotein 5 (GP5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Glycoprotein 5 (GP5) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | 0.1 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O08770 |
| Gene ID | 25259 |
| NCBI Accession | NP_036927.1 |
| Alias | GPV,CD42d,Platelet glycoprotein V,GPV,Glycoprotein 5,CD42d |
| Background | Elisa kits for GP5 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Glycoprotein V (GP5) is a key platelet membrane protein that functions as a part of the GPIb-IX-V complex, a receptor system primarily responsible for mediating platelet adhesion during vascular injury. This complex is crucial for the initial steps of platelet plug formation, which is essential in the process of hemostasis, particularly in the high-shear conditions of arterial blood flow. GP5 serves as an accessory component in the complex, complementing the roles of other glycoproteins like GPIbα (GP1BA), GPIbβ (GP1BB), and GPIX (GP9). The GPIb-IX-V complex, including GP5, binds to von Willebrand factor (vWF), which facilitates platelet tethering to the damaged endothelium under conditions of high shear stress. Although GP5 is not the primary binding site for vWF (that role belongs to GP1BA), it contributes to the structural integrity and function of the receptor. GP5 may also interact with other ligands and is thought to regulate the binding activity of the GPIb-IX-V complex.
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