Rat gamma-Glutamyltransferase 5 (GGT5) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Rat gamma-Glutamyltransferase 5 (GGT5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525249
tested applications
ELISA
Description
Rat gamma-Glutamyltransferase 5 (GGT5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Gamma-glutamyltransferase 5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | gamma-Glutamyltransferase 5 (GGT5) |
Reactivity | Rat |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q9QWE9 |
Alias | GGL,GGT 5,GGT-REL,GGTLA1 |
Background | Elisa kits for GGT5 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Gamma-glutamyltransferase 5 (GGT5) is an enzyme that cleaves gamma-glutamyl bonds in glutathione and other gamma-glutamyl compounds, facilitating glutathione metabolism and amino acid transport GGT5 is primarily expressed in the kidney, liver, and immune cells where it regulates extracellular glutathione breakdown and amino acid uptake for cellular antioxidant defense and detoxification pathways GGT5 plays a role in maintaining redox homeostasis by recycling glutathione, a key molecule for combating reactive oxygen species (ROS) Dysregulation of GGT5 expression has been associated with inflammatory conditions, cardiovascular diseases, and metabolic disorders Elevated GGT5 levels have also been observed in cancers, such as liver and renal cancers, where enhanced glutathione metabolism supports tumor progression and resistance to oxidative stress Additionally, GGT5 is involved in immune responses, as it regulates lymphocyte activation and macrophage function Its role in glutathione metabolism, cellular detoxification, and immune regulation underscores its importance in maintaining cellular health and redox balance across various physiological and pathological conditions
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