Rat gamma-Glutamyltransferase 5 (GGT5) ELISA Kit

Este producto es parte de GGT - Gamma-Glutamyltransferase
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat gamma-Glutamyltransferase 5 (GGT5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525249
tested applications
ELISA

Description

Rat gamma-Glutamyltransferase 5 (GGT5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Gamma-glutamyltransferase 5 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
gamma-Glutamyltransferase 5 (GGT5)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9QWE9
Alias
GGL,GGT 5,GGT-REL,GGTLA1
Background
Elisa kits for GGT5
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Gamma-glutamyltransferase 5 (GGT5) is an enzyme that cleaves gamma-glutamyl bonds in glutathione and other gamma-glutamyl compounds, facilitating glutathione metabolism and amino acid transport GGT5 is primarily expressed in the kidney, liver, and immune cells where it regulates extracellular glutathione breakdown and amino acid uptake for cellular antioxidant defense and detoxification pathways GGT5 plays a role in maintaining redox homeostasis by recycling glutathione, a key molecule for combating reactive oxygen species (ROS) Dysregulation of GGT5 expression has been associated with inflammatory conditions, cardiovascular diseases, and metabolic disorders Elevated GGT5 levels have also been observed in cancers, such as liver and renal cancers, where enhanced glutathione metabolism supports tumor progression and resistance to oxidative stress Additionally, GGT5 is involved in immune responses, as it regulates lymphocyte activation and macrophage function Its role in glutathione metabolism, cellular detoxification, and immune regulation underscores its importance in maintaining cellular health and redox balance across various physiological and pathological conditions

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