gamma-Glutamyltransferase 5 (GGT5) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
gamma-Glutamyltransferase 5 (GGT5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122822
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the GGT5 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | gamma-Glutamyltransferase 5 (GGT5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC073999 |
| Alias | GGL,GGT 5,GGT-REL,GGTLA1 |
| Background | Antibody anti-GGT5 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Gamma-glutamyltransferase 5 (GGT5) is an enzyme that cleaves gamma-glutamyl bonds in glutathione and other gamma-glutamyl compounds, facilitating glutathione metabolism and amino acid transport GGT5 is primarily expressed in the kidney, liver, and immune cells where it regulates extracellular glutathione breakdown and amino acid uptake for cellular antioxidant defense and detoxification pathways GGT5 plays a role in maintaining redox homeostasis by recycling glutathione, a key molecule for combating reactive oxygen species (ROS) Dysregulation of GGT5 expression has been associated with inflammatory conditions, cardiovascular diseases, and metabolic disorders Elevated GGT5 levels have also been observed in cancers, such as liver and renal cancers, where enhanced glutathione metabolism supports tumor progression and resistance to oxidative stress Additionally, GGT5 is involved in immune responses, as it regulates lymphocyte activation and macrophage function Its role in glutathione metabolism, cellular detoxification, and immune regulation underscores its importance in maintaining cellular health and redox balance across various physiological and pathological conditions
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