Rat Gamma-Adducin (ADD3) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADD3
proveedor
Abbexareference
abx501108Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Gamma-Adducin (ADD3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Gamma-adducin concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADD3 encodes gamma-adducin, a ubiquitously expressed cytoskeletal protein that cooperates with alpha- and beta-adducins to modulate the actin-spectrin network and stabilize cellular membranes. It is most abundantly expressed in the liver, kidneys, and vascular endothelium, where it regulates cell shape, motility, and membrane mechanical properties. Gamma-adducin is also implicated in intracellular signaling and vascular integrity, playing a role in processes such as angiogenesis and endothelial barrier function. Variants in ADD3 have been associated with conditions such as hypertension and vascular diseases due to its role in modulating ion transport and vascular permeability. Dysregulation of gamma-adducin impacts cellular architecture and signaling pathways, contributing to diseases involving structural or functional defects in the actin-spectrin cytoskeleton. Its broad expression and functional versatility highlight its importance in cellular and systemic homeostasis.
Características del producto
category
ELISA Kits
immunogen target
Gamma-Adducin (ADD3)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ADDL,CPSQ3,ADDUCIN 3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADD3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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