Rat Galanin Receptor Type 3 (GALR3) ELISA Kit
611€ (96 tests)
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935106861
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name
Rat Galanin Receptor Type 3 (GALR3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx354075
tested applications
ELISA
Description
Rat Galanin Receptor Type 3 (GALR3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Galanin Receptor Type 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Galanin Receptor Type 3 (GALR3) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | 0.47 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O88626 |
| Gene ID | 29235 |
| Alias | GALR3,GALR3,Galnr3,GAL3 receptor |
| Background | Elisa kits for GALR3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
GALR3 is a G protein-coupled receptor that primarily couples to Gi/o proteins, mediating the inhibitory effects of galanin by reducing intracellular cAMP levels and modulating ion channels. GALR3 is expressed in brain regions such as the hypothalamus, hippocampus, and amygdala, where it regulates mood, feeding, and reward processing. GALR3 activation has been implicated in the regulation of depression and anxiety, where it exerts an inhibitory effect on neuronal excitability and neurotransmitter release. In pain pathways, GALR3 contributes to the modulation of nociceptive signaling, though its role appears less defined compared to GALR1 and GALR2. GALR3 is also expressed in peripheral tissues, where it may influence cardiovascular function and immune responses. In cancer, GALR3 has been associated with tumor progression, particularly in breast and prostate cancers, where galanin signaling promotes cell survival and proliferation. Dysregulation of GALR3 contributes to mood disorders, neuropathic pain, and tumor growth. Its role in neuronal inhibition and emotional regulation makes GALR3 a promising target for treating mood disorders, pain, and cancer progression.
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