Rat Fibroblast Growth Factor 2 (FGF2) Protein (Active)

Este producto es parte de FGF2 - Fibroblast Growth Factor 2
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247€ (10 µg)

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935106861
info@markelab.com
name
Rat Fibroblast Growth Factor 2 (FGF2) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx693935
tested applications
SDS-PAGE

Description

Rat Fibroblast Growth Factor 2 (FGF2) Protein is a recombinant protein from Rat produced in E. coli. Recombinant Rat Fibroblast growth factor 2/Fibroblast Growth Factor Basic is produced by our E.coli expression system and the target gene encoding Ala11-Ser154 is expressed.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Fibroblast Growth Factor 2 (FGF2)
Host
E. coli
Origin
Rat
Observed MW
Molecular Weight: 16.2 kDa
Sequence Fragment: Ala11-Ser154
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
20mM PB, 150mM NaCl, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
P13109
Alias
FGF-2,Basic fibroblast growth factor,Bfgf,Heparin-binding growth factor 2 (HBGF-2),FGFB
Background
Protein FGF2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

FGF2, also referred to as basic fibroblast growth factor (bFGF), is a growth factor involved in critical cellular processes, including angiogenesis, wound healing, and tissue repair It binds to FGF receptors (FGFRs) and activates pathways like Ras/MAPK and PI3K/AKT, which regulate cell proliferation, survival, and differentiation FGF2 is expressed in endothelial cells, fibroblasts, and smooth muscle cells, where it drives vascularization during tissue repair and development It promotes stem cell maintenance and supports neurogenesis by enhancing neuronal survival and regeneration Dysregulated FGF2 contributes to tumor growth, angiogenesis, and metastasis in cancers such as breast cancer and glioblastoma Targeting FGF2 signaling is a therapeutic strategy in cancer treatment, tissue regeneration, and ischemic conditions

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