Rat Fibroblast Growth Factor 2 (FGF2) Protein (Active)

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Description
Rat Fibroblast Growth Factor 2 (FGF2) Protein is a recombinant protein from Rat produced in E. coli. Recombinant Rat Fibroblast growth factor 2/Fibroblast Growth Factor Basic is produced by our E.coli expression system and the target gene encoding Ala11-Ser154 is expressed.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Fibroblast Growth Factor 2 (FGF2) |
Host | E. coli |
Origin | Rat |
Observed MW | Molecular Weight: 16.2 kDa Sequence Fragment: Ala11-Ser154 |
Expression | Recombinant |
Purity | > 95% (SDS-PAGE) |
Size 1 | 10 µg |
Size 2 | 50 µg |
Form | Lyophilized |
Tested Applications | SDS-PAGE |
Buffer | 20mM PB, 150mM NaCl, pH7.4. |
Availability | Shipped within 5-15 working days. |
Storage | Store at < -20°C. |
Dry Ice | No |
UniProt ID | P13109 |
Alias | FGF-2,Basic fibroblast growth factor,Bfgf,Heparin-binding growth factor 2 (HBGF-2),FGFB |
Background | Protein FGF2 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
FGF2, also referred to as basic fibroblast growth factor (bFGF), is a growth factor involved in critical cellular processes, including angiogenesis, wound healing, and tissue repair It binds to FGF receptors (FGFRs) and activates pathways like Ras/MAPK and PI3K/AKT, which regulate cell proliferation, survival, and differentiation FGF2 is expressed in endothelial cells, fibroblasts, and smooth muscle cells, where it drives vascularization during tissue repair and development It promotes stem cell maintenance and supports neurogenesis by enhancing neuronal survival and regeneration Dysregulated FGF2 contributes to tumor growth, angiogenesis, and metastasis in cancers such as breast cancer and glioblastoma Targeting FGF2 signaling is a therapeutic strategy in cancer treatment, tissue regeneration, and ischemic conditions
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