Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit

Este producto es parte de FGF19 - Fibroblast Growth Factor 19
Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit
767€ (96 tests)

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Name
Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx258221
Tested Applications
ELISA

Description

Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Fibroblast Growth Factor 19 (FGF19) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Fibroblast Growth Factor 19 (FGF19)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Competitive
Test Range
12.5 pg/ml - 200 pg/ml
Sensitivity
< 5.2 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8VI81
Gene ID
170582
Alias
FGF-19
Background
Elisa Kits for: FGF19
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

FGF19 is a metabolic hormone primarily produced in the ileum of the small intestine in response to bile acid signaling where it regulates bile acid homeostasis by suppressing cholesterol 7α-hydroxylase (CYP7A1) expression in the liver FGF19 also promotes glucose metabolism, lipid homeostasis, and energy expenditure through signaling pathways involving its receptor FGFR4 and the co-receptor β-Klotho Dysregulation of FGF19 has been linked to non-alcoholic fatty liver disease (NAFLD), insulin resistance, and obesity Elevated FGF19 levels are also observed in liver cancers such as hepatocellular carcinoma (HCC) where its overactivation promotes tumor growth by driving cell proliferation and survival FGF19 analogs are being explored as therapies for metabolic disorders, including type 2 diabetes and dyslipidemia

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