Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit
![Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fcatalog%2FGraphs%2F29%2Fabx258221%2Fabx258221_Rat_Fibroblast_Growth_Factor_15_FGF15_ELISA_Kit_graph-250x250.png&w=3840&q=75)
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935106861
info@markelab.com
Precio
737.5€ (96 tests)
Elisa Kits FGF19
proveedor
Abbexareference
abx258221Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Fibroblast Growth Factor 19 (FGF19) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
FGF19 is a metabolic hormone primarily produced in the ileum of the small intestine in response to bile acid signaling where it regulates bile acid homeostasis by suppressing cholesterol 7α-hydroxylase (CYP7A1) expression in the liver FGF19 also promotes glucose metabolism, lipid homeostasis, and energy expenditure through signaling pathways involving its receptor FGFR4 and the co-receptor β-Klotho Dysregulation of FGF19 has been linked to non-alcoholic fatty liver disease (NAFLD), insulin resistance, and obesity Elevated FGF19 levels are also observed in liver cancers such as hepatocellular carcinoma (HCC) where its overactivation promotes tumor growth by driving cell proliferation and survival FGF19 analogs are being explored as therapies for metabolic disorders, including type 2 diabetes and dyslipidemia
Características del producto
category
ELISA Kits
immunogen target
Fibroblast Growth Factor 19 (FGF19)
reactivity
Rat
test range
12.5 pg/ml - 200 pg/ml
sensitivity
< 5.2 pg/ml
assay type
Competitive
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
FGF-19
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FGF19
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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