Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit

Este producto es parte de FGF19 - Fibroblast Growth Factor 19
Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits FGF19

proveedor

Abbexa

reference

abx155517

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Fibroblast Growth Factor 19 (FGF19) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Fibroblast Growth Factor 19 (FGF19) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Fibroblast Growth Factor 19 (FGF19)No significant cross-reactivity or interference between Fibroblast Growth Factor 19 (FGF19) and analogues was observed.


Background

FGF19 is a metabolic hormone primarily produced in the ileum of the small intestine in response to bile acid signaling where it regulates bile acid homeostasis by suppressing cholesterol 7α-hydroxylase (CYP7A1) expression in the liver FGF19 also promotes glucose metabolism, lipid homeostasis, and energy expenditure through signaling pathways involving its receptor FGFR4 and the co-receptor β-Klotho Dysregulation of FGF19 has been linked to non-alcoholic fatty liver disease (NAFLD), insulin resistance, and obesity Elevated FGF19 levels are also observed in liver cancers such as hepatocellular carcinoma (HCC) where its overactivation promotes tumor growth by driving cell proliferation and survival FGF19 analogs are being explored as therapies for metabolic disorders, including type 2 diabetes and dyslipidemia

Características del producto

category

ELISA Kits


immunogen target

Fibroblast Growth Factor 19 (FGF19)


reactivity

Rat


test range

9.38 pg/ml - 600 pg/ml


sensitivity

< 3.8 pg/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

FGF-19


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

FGF19


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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