Rat Contactin 4 (CNTN4) ELISA Kit

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552.5€ (96 tests)

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935106861
info@markelab.com
name
Rat Contactin 4 (CNTN4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx256814
tested applications
ELISA

Description

Rat Contactin 4 (CNTN4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Contactin 4 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetContactin 4 (CNTN4)
ReactivityRat
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.312 ng/ml - 20 ng/ml
Sensitivity0.19 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma, tissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ62845
Gene ID116658
NCBI AccessionNP_446331.1, XP_017447884.1, XP_017447885.1
AliasAXCAM,BIG-2, Brain-derived immunoglobulin superfamily protein 2,Contactin-4
BackgroundElisa kits for CNTN4
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Contactin 4 (CNTN4), a GPI-anchored member of the immunoglobulin superfamily, is predominantly expressed in the central nervous system, where it regulates neuronal development and synaptic connectivity. CNTN4 is involved in axon guidance, neuronal migration, and synapse formation by mediating homophilic and heterophilic cell-cell interactions. It interacts with other neural cell adhesion molecules and receptors to establish neural circuits during development, particularly in the auditory and visual systems. CNTN4 has been implicated in neurodevelopmental disorders, including autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), where its dysregulation affects neural connectivity and cognitive function. Structural studies reveal that CNTN4 contains extracellular immunoglobulin-like and fibronectin type III domains, which facilitate dynamic interactions essential for its role in neural development. Beyond its role in the nervous system, CNTN4 is also expressed in non-neural tissues, where it may contribute to cell adhesion and signaling in developmental and pathological contexts.

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