Rat CNTN4(Contactin 4) ELISA Kit

Este producto es parte de CNTN - contactin
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935106861
info@markelab.com
name
Rat CNTN4(Contactin 4) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0846

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Product specifications

CategoryELISA Kits
Reactivityrat
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich ELISA, Double Antibody
Test Range0.313-20ng/ml
Size 196T
Sample TypeSerum,Plasma,Tissue homogenates,Other biological fluids
AvailabilityShipped within 10-14 working days.
Storage2-8 °C for 6 months
UniProt IDQ62845
AliasAXCAM,BIG-2, Brain-derived immunoglobulin superfamily protein 2,Contactin-4
BackgroundElisa Kits CNTN4
StatusRUO

Contactin 4 (CNTN4), a GPI-anchored member of the immunoglobulin superfamily, is predominantly expressed in the central nervous system, where it regulates neuronal development and synaptic connectivity. CNTN4 is involved in axon guidance, neuronal migration, and synapse formation by mediating homophilic and heterophilic cell-cell interactions. It interacts with other neural cell adhesion molecules and receptors to establish neural circuits during development, particularly in the auditory and visual systems. CNTN4 has been implicated in neurodevelopmental disorders, including autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), where its dysregulation affects neural connectivity and cognitive function. Structural studies reveal that CNTN4 contains extracellular immunoglobulin-like and fibronectin type III domains, which facilitate dynamic interactions essential for its role in neural development. Beyond its role in the nervous system, CNTN4 is also expressed in non-neural tissues, where it may contribute to cell adhesion and signaling in developmental and pathological contexts.

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Rat CNTN4(Contactin 4) ELISA Kit | ER0846