Rat Cell Adhesion Molecule 2 (CADM2) ELISA Kit
715€ (96 tests)
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name
Rat Cell Adhesion Molecule 2 (CADM2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx504629
tested applications
ELISA
Description
Rat Cell Adhesion Molecule 2 (CADM2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Cell Adhesion Molecule 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cell Adhesion Molecule 2 (CADM2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q1WIM2 |
| Gene ID | 360687 |
| Alias | NECL3,IGSF4D,Necl-3,synCAM2,SynCAM 2,SynCAM-2,Synaptic cell adhesion molecule 2,Nectin-like protein 3,Immunoglobulin superfamily member 4D |
| Background | Elisa kits for CADM2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CADM2, also known as SynCAM2, is a neuronal cell adhesion molecule involved in synaptic organization, axon guidance, and neural circuit formation. It is predominantly expressed in the central nervous system, where it contributes to the development and maintenance of synaptic connections, particularly in excitatory synapses. CADM2 plays a critical role in long-term potentiation (LTP) and synaptic plasticity, processes essential for learning and memory. It also influences axonal growth and guidance by mediating interactions between neurons and glial cells. CADM2 has been implicated in neuropsychiatric disorders, including autism spectrum disorder (ASD) and schizophrenia, where its dysregulation disrupts neural connectivity and cognitive function. Structurally, CADM2 contains extracellular immunoglobulin domains that mediate homophilic and heterophilic binding, enabling synaptic adhesion and signaling. It interacts with intracellular scaffolding proteins and signaling molecules to regulate cytoskeletal dynamics and intracellular signaling pathways. Beyond the nervous system, CADM2 is also expressed in reproductive tissues and has been linked to processes such as spermatogenesis. Emerging evidence suggests that CADM2 may influence metabolic regulation, with genetic variants associated with traits like body weight and energy expenditure.
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