Rat CD109 Antigen (CD109) Protein
Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein CD109
proveedor
Abbexareference
abx168522Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Cluster Of Differentiation 109 Protein is a recombinant Rat protein expressed in E. coli.
Background
CD109 molecule is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein that plays a role in regulating various cellular processes, including immune response and hematopoiesis CD109 is expressed on a variety of cells, including T-cells, endothelial cells, and platelets, and functions as a negative regulator of the transforming growth factor-beta (TGF-β) signaling pathway, which is critical for cell proliferation, differentiation, and immune response modulation By interacting with TGF-β receptors, CD109 modulates TGF-β signaling, potentially inhibiting excessive fibrosis or immune suppression Dysregulation of CD109 expression has been linked to certain cancers, where it can enhance tumor cell survival by suppressing anti-tumor immune responses It is also associated with autoimmune diseases, where its role in immune modulation can influence the development of inflammatory conditions Recent studies have explored CD109 as a potential biomarker for various diseases, including cancer and autoimmune disorders, emphasizing its importance in cellular regulation and immune homeostasis
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
CD109 Antigen (CD109)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 30.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile719-Arg965 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CD109
dry ice
No
availability
Shipped within 5-7 working days.
alias
p180,r150,CPAMD7,Platelet-specific Gov antigen,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Human CD109(CD109 antigen) ELISA Kit
proveedor
FineTestreference
EH1701reactivity
humanstatus
RUOPrecio a consultar
Ver másanti- CD109 antibody
proveedor
FineTestreference
FNab01408Tested Applications
ELISA, WBreactivity
humanstatus
RUOclonality
polyclonalModulates negatively TGFB1 signaling in keratinocytes.
Precio a consultar
Ver másCD109 Antigen (CD109) Antibody
proveedor
Abbexareference
abx025814Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalCD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on th...
292.5€ (80 µl)
Ver más