Rat Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) Protein
208€ (10 µg)
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935106861
info@markelab.com
name
Rat Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065727
tested applications
WB, SDS-PAGE
Description
Recombinant Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 17.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser273-Leu416 Tag: N-terminal His tag |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q63111 |
| Alias | CEA,CGM1,W264,W282,CD66D,CGM1a,CGM1,Carcinoembryonic antigen-related cell adhesion molecule 3 |
| Background | Protein CEACAM3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CEACAM3, also known as CD66d, is part of the carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), a subgroup within the immunoglobulin superfamily (IgSF). CEACAM3 is primarily expressed on granulocytes, particularly neutrophils, and plays a crucial role in the innate immune response, specifically in defending against bacterial infections. Unlike other CEACAM family members that are primarily involved in cell-cell adhesion and tumor biology, CEACAM3 is highly specialized for recognizing and mediating the phagocytosis of bacteria, particularly pathogenic Neisseria species, Haemophilus influenzae, and Moraxella catarrhalis. CEACAM3 functions as an opsonin-independent phagocytic receptor, enabling neutrophils to directly recognize and engulf bacteria without the need for antibody or complement opsonization. This receptor is a critical component of the host defense system against specific bacterial pathogens that have evolved to exploit CEACAM family proteins to adhere to host cells.
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