Rat C-Type Lectin Domain Family 13 Member A (CD302) Protein
1235€ (100 µg)
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935106861
info@markelab.com
name
Rat C-Type Lectin Domain Family 13 Member A (CD302) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690906
tested applications
SDS-PAGE
Description
Rat CD302 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat CD302 (Met1-His165) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CD302 |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: 43.7 kDa Sequence Fragment: Met1-His165 Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_001013938.1 |
| Alias | C-type lectin domain family 13 member A,DCL1,DCL-1,BIMLEC,CLEC13A,C-type lectin BIMLEC,DEC205-associated C-type lectin 1 |
| Background | Protein CD302 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD302, also known as the CD302 molecule or CLEC13A, is a protein within the C-type lectin receptor (CLR) family and plays a role in the immune system. Expressed predominantly on dendritic cells, monocytes, macrophages, and granulocytes, CD302 is a transmembrane receptor that is thought to facilitate immune cell migration, adhesion, and pathogen recognition. Structurally, CD302 shares characteristics with other C-type lectins, specifically with a C-type lectin-like domain (CTLD) that mediates interactions with carbohydrates on microbial surfaces. As a receptor, CD302 is involved in various processes including endocytosis and phagocytosis, making it an essential component of immune cell function and pathogen defense mechanisms. CD302’s expression across various immune cell types suggests it plays a broad role in both innate and adaptive immune responses, particularly in antigen-presenting cells (APCs) like macrophages and dendritic cells. Given its cell-surface localization and involvement in binding to carbohydrate structures, CD302 is of significant interest in studies related to host-pathogen interactions, immune surveillance, and potentially in autoimmune and inflammatory diseases.
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