Rat Bone Morphogenetic Protein Receptor 1A (BMPR1A) Protein
234€ (10 µg)
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Name
Rat Bone Morphogenetic Protein Receptor 1A (BMPR1A) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx166010
Tested Applications
WB, SDS-PAGE
Description
Rat Bone Morphogenetic Protein Receptor 1A is a recombinant Rat protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Bone Morphogenetic Protein Receptor 1A (BMPR1A) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Gln24-Arg152 Tag: N-terminal His tag |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 18.0 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q78EA7 |
| Alias | Activin receptor-like kinase 3,ALK3,SKR5,ALK-3,CD292,ACVRLK3,BMPR-1A,Serine/threonine-protein kinase receptor R5 |
| Background | Protein BMPR1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
Bone morphogenetic protein receptor type 1A (BMPR1A) is a receptor for the bone morphogenetic proteins (BMPs), a subgroup of the transforming growth factor-beta (TGF-β) superfamily. BMPs are growth factors and cytokines that play critical roles in embryonic development, skeletal formation, organogenesis, and tissue homeostasis. BMPR1A, also known as ALK3 (Activin receptor-like kinase 3), specifically mediates BMP signaling by interacting with BMP ligands to activate intracellular pathways, influencing processes such as cell growth, differentiation, apoptosis, and repair. This receptor is essential for bone and cartilage development and has critical roles in several cell types across various tissues, with particularly strong influence in skeletal, cardiac, and gastrointestinal systems.
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