Rat Bombesin Receptor Subtype-3 (BRS3) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Bombesin Receptor Subtype-3 (BRS3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx391029
tested applications
ELISA
Description
Rat Bombesin Receptor Subtype-3 (BRS3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat BRS3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Bombesin Receptor Subtype-3 (BRS3) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8K418 |
| Gene ID | 260319 |
| Alias | BRS3,BB3 receptor,bb3,bombesin receptor subtype-3, bombesin like receptor 3,BB3R, BBR3 |
| Background | Elisa kits for BRS3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Bombesin Receptor Subtype 3 (BRS3) is an orphan G-protein-coupled receptor within the bombesin receptor family, though its endogenous ligand remains unidentified. BRS3 is predominantly expressed in the central nervous system, including the hypothalamus, as well as in adipose tissue and certain peripheral organs. BRS3 is primarily involved in energy homeostasis and metabolic regulation, as it modulates thermogenesis, appetite control, and body weight. Activation of BRS3 increases energy expenditure by stimulating pathways in brown adipose tissue, enhancing heat production and combating obesity. In addition to energy regulation, BRS3 influences glucose metabolism and insulin sensitivity, suggesting potential roles in type 2 diabetes treatment. Furthermore, BRS3 signaling regulates blood pressure, contributing to cardiovascular homeostasis. Dysregulation of BRS3 expression has been linked to obesity, metabolic syndrome, and certain cancers, particularly lung cancer and prostate cancer, where it may facilitate tumor proliferation and survival. Given its critical roles in metabolism, thermogenesis, and cancer biology, BRS3 has emerged as a potential therapeutic target for metabolic diseases and oncology. Ongoing studies aim to identify its natural ligand and develop pharmacological agonists or antagonists to exploit its therapeutic potential.
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