935106861
info@markelab.com
Precio
687.5€ (96 tests)
Rat Bile Salt Export Pump (ABCB11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Bile Salt Export Pump (ABCB11) concentrations in tissue homogenates, cell lysates and other biological fluids.
ABCB11, also known as the bile salt export pump (BSEP), is an essential transporter located on the canalicular membrane of hepatocytes. It is responsible for exporting bile salts from the liver into bile, a critical step in the digestion and absorption of dietary fats and the excretion of waste products. ABCB11 is ATP-dependent and plays a vital role in maintaining bile flow and preventing bile salt accumulation, which can damage liver cells. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis type 2 (PFIC2), a severe liver disorder characterized by impaired bile salt secretion and liver damage. Dysregulation or inhibition of ABCB11 is also implicated in drug-induced cholestasis and liver injury. Its essential function in bile production and liver health makes it a critical target for understanding and treating cholestatic diseases.
ELISA Kits
Bile Salt Export Pump (ABCB11)
Rat
78 pg/ml - 5000 pg/ml
< 33 pg/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
ABCB11,ABC16,BRIC2,BSEP,PFIC-2,PFIC2,PGY4,SPGP
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ABCB11
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Precio a consultar
Ver másABCB11 Antibody is a Rabbit Polyclonal Antibody against ABCB11.
175€ (20 µl)
Ver másATP Binding Cassette Transporter B11 Antibody is a Rabbit Polyclonal against ATP Binding Cassette Transporter B11.
275€ (100 µl)
Ver más