Rat Bcl10 (B-cell lymphoma/leukemia 10) ELISA Kit

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935106861
info@markelab.com
name
Rat Bcl10 (B-cell lymphoma/leukemia 10) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0707
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | Rat |
Detection Method | Colorimetric |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.156-10ng/ml |
Sensitivity | 0.094ng/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q9QYN5 |
Alias | CARMEN,CIPER,CLAP,IMD37,c-E10 Me10,CARD-containing molecule enhancing NF-kappa-B,CARD-like apoptotic protein, hCLAP |
Background | Elisa kits for Bcl10 |
Status | RUO |
B-cell lymphoma/leukemia 10 (BCL10) is an essential signaling molecule involved in the regulation of immune cell activation, particularly in T-cell and B-cell responses BCL10 functions as a scaffolding protein in the activation of the NF-κB pathway, which is crucial for regulating inflammation, immune responses, and cell survival BCL10 forms a complex with other proteins, such as MALT1, to initiate signaling cascades that lead to immune cell activation and proliferation Its dysregulation has been linked to lymphoid malignancies, such as MALT lymphoma, where mutations or overexpression of BCL10 promote cancer cell proliferation and survival BCL10 is also involved in the regulation of apoptosis and cell differentiation, particularly in the context of immune cell maturation In addition to its role in immune cells, BCL10 has been shown to influence inflammatory diseases and autoimmunity, making it a potential target for therapeutic intervention
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