Rat Bcl-2-Related Ovarian Killer Protein (BOK) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for BOK
proveedor
Abbexareference
abx391013Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Bcl-2-Related Ovarian Killer Protein (BOK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat BOK concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Bcl-2-related ovarian killer protein (BOK) is a pro-apoptotic member of the Bcl-2 family that plays a critical role in mediating apoptosis through mitochondrial pathways BOK induces cell death by interacting with other Bcl-2 family members, promoting mitochondrial outer membrane permeabilization and facilitating the release of apoptotic factors like cytochrome c, which activate caspases and lead to programmed cell death Unlike other Bcl-2 family members, BOK is not regulated by the BH3 domain and has a unique role in apoptosis, particularly in ovarian cells BOK’s expression is tightly controlled in healthy tissues, and its dysregulation has been associated with various cancers, where it can influence tumor cell survival, apoptosis resistance, and cancer progression Additionally, BOK has been implicated in regulating neuronal cell death, and its role in maintaining cellular homeostasis under stress conditions suggests it may be a target for therapeutic strategies aimed at inducing apoptosis in tumor cells or protecting against neurodegeneration
Características del producto
category
ELISA Kits
immunogen target
Bcl-2-Related Ovarian Killer Protein (BOK)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Hbok,BOKL,BCL2L9,Bcl-2-like protein 9,Bcl2-L-9,Bcl-2-related ovarian killer protein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
BOK
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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