Rat BAG Family Molecular Chaperone Regulator 5 (BAG5) Protein

Este producto es parte de BAG - BAG cochaperone 1
Rat BAG Family Molecular Chaperone Regulator 5 (BAG5) Protein

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935106861

info@markelab.com

Precio

221€ (10 µg)

Protein BAG5

proveedor

Abbexa

reference

abx650649

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat BAG5 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

BAG cochaperone 5 (BAG5) is a member of the BAG family of cochaperones that interacts with heat shock proteins, particularly HSP70, to regulate protein folding, degradation, and cellular stress responses BAG5 plays a crucial role in managing the cellular proteostasis network, especially under stress conditions It has been implicated in modulating apoptosis, where it acts as a survival factor by influencing cell death pathways BAG5 regulates protein turnover by promoting the degradation of misfolded proteins and supporting cellular adaptation to oxidative stress Its expression has been linked to neurodegenerative diseases, where impaired protein quality control leads to toxic protein aggregates BAG5 is also involved in regulating muscle cell function and has been shown to play a role in protecting cells from atrophy and degeneration in muscle tissues Studies indicate that BAG5 is associated with cancer biology, where it can prevent apoptosis in tumor cells, contributing to resistance to chemotherapy and promoting tumor growth

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

BAG Family Molecular Chaperone Regulator 5 (BAG5)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 28.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Ser217 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

BAG5


dry ice

No


availability

Shipped within 5-7 working days.


alias

BAG-5,CMD2F,Bcl-2-associated athanogene 5,BAG family molecular chaperone regulator 5


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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