Rat BAG Family Molecular Chaperone Regulator 5 (BAG5) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein BAG5
proveedor
Abbexareference
abx650649Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat BAG5 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
BAG cochaperone 5 (BAG5) is a member of the BAG family of cochaperones that interacts with heat shock proteins, particularly HSP70, to regulate protein folding, degradation, and cellular stress responses BAG5 plays a crucial role in managing the cellular proteostasis network, especially under stress conditions It has been implicated in modulating apoptosis, where it acts as a survival factor by influencing cell death pathways BAG5 regulates protein turnover by promoting the degradation of misfolded proteins and supporting cellular adaptation to oxidative stress Its expression has been linked to neurodegenerative diseases, where impaired protein quality control leads to toxic protein aggregates BAG5 is also involved in regulating muscle cell function and has been shown to play a role in protecting cells from atrophy and degeneration in muscle tissues Studies indicate that BAG5 is associated with cancer biology, where it can prevent apoptosis in tumor cells, contributing to resistance to chemotherapy and promoting tumor growth
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
BAG Family Molecular Chaperone Regulator 5 (BAG5)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 28.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Ser217 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
BAG5
dry ice
No
availability
Shipped within 5-7 working days.
alias
BAG-5,CMD2F,Bcl-2-associated athanogene 5,BAG family molecular chaperone regulator 5
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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