Rat BAG Family Molecular Chaperone Regulator 5 (BAG5) ELISA Kit
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Description
Rat BAG Family Molecular Chaperone Regulator 5 (BAG5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat BAG family molecular chaperone regulator 5 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | BAG Family Molecular Chaperone Regulator 5 (BAG5) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5QJC9 |
| Alias | BAG-5,CMD2F,Bcl-2-associated athanogene 5,BAG family molecular chaperone regulator 5 |
| Background | Elisa kits for BAG5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
BAG cochaperone 5 (BAG5) is a member of the BAG family of cochaperones that interacts with heat shock proteins, particularly HSP70, to regulate protein folding, degradation, and cellular stress responses BAG5 plays a crucial role in managing the cellular proteostasis network, especially under stress conditions It has been implicated in modulating apoptosis, where it acts as a survival factor by influencing cell death pathways BAG5 regulates protein turnover by promoting the degradation of misfolded proteins and supporting cellular adaptation to oxidative stress Its expression has been linked to neurodegenerative diseases, where impaired protein quality control leads to toxic protein aggregates BAG5 is also involved in regulating muscle cell function and has been shown to play a role in protecting cells from atrophy and degeneration in muscle tissues Studies indicate that BAG5 is associated with cancer biology, where it can prevent apoptosis in tumor cells, contributing to resistance to chemotherapy and promoting tumor growth
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