Rat Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits TNFSF13B
proveedor
Abbexareference
abx155245Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat B-Cell Activating Factor (BAFF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat B-Cell Activating Factor (BAFF) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of B-Cell Activating Factor (BAFF)No significant cross-reactivity or interference between B-Cell Activating Factor (BAFF) and analogues was observed.
Background
TNFSF13B, commonly known as BAFF (B-cell activating factor), is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is critical for B cell survival, maturation, and immune function. This ligand is primarily produced by myeloid cells, such as monocytes, macrophages, and dendritic cells, but can also be secreted by activated T cells. BAFF plays a pivotal role in maintaining peripheral B cell populations, supporting antibody production, and promoting immune tolerance. It interacts with specific receptors on B cells and related immune cells, including BAFF-R, TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor), and BCMA (B Cell Maturation Antigen), to initiate intracellular signaling pathways crucial for B cell homeostasis and function. Dysregulation of BAFF expression or receptor binding is associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis, and rheumatoid arthritis.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B)
reactivity
Rat
test range
78 pg/ml - 5000 pg/ml
sensitivity
< 27 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Tumor necrosis factor ligand superfamily member 13B,DTL,BAFF,BLYS,CD257,TALL1,THANK,ZTNF4,TALL-1,TNLG7A,TNFSF20,B lymphocyte stimulator,BLyS,Dendritic cell-derived TNF-like molecule,TNF- and APOL-related leukocyte expressed ligand 1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
TNFSF13B
dry ice
No
uniprot id
NCBI accession
NP_001382650.1
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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