Rat ATP Binding Cassette Transporter A2 (ABCA2) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ABCA2
proveedor
Abbexareference
abx500405Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat ATP Binding Cassette Transporter A2 (ABCA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat ATP-binding cassette sub-family A member 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ABCA2 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid metabolism and intracellular cholesterol transport. It is primarily expressed in the brain, liver, and macrophages, where it plays a role in maintaining cellular lipid homeostasis and the transport of sterols and sphingolipids. Structurally, ABCA2 contains two transmembrane domains and two nucleotide-binding domains, which use ATP hydrolysis to drive lipid translocation across intracellular membranes. ABCA2 is implicated in myelin formation and neuronal function, highlighting its importance in the central nervous system. Dysregulation of ABCA2 expression has been associated with neurodegenerative diseases, such as Alzheimer’s disease, and certain cancers, where it may contribute to drug resistance by altering cellular lipid composition.
Características del producto
category
ELISA Kits
immunogen target
ATP Binding Cassette Transporter A2 (ABCA2)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
MRX,MXR,ABCP,BCRP,BMDP,MXR1,ABC15,BCRP1,CD338
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ABCA2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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