Rat Aryl Hydrocarbon Receptor Interacting Protein (AIP) ELISA Kit
611€ (96 tests)
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Name
Rat Aryl Hydrocarbon Receptor Interacting Protein (AIP) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx353504
Tested Applications
ELISA
Description
Rat Aryl Hydrocarbon Receptor Interacting Protein (AIP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aryl Hydrocarbon Receptor Interacting Protein (AIP) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Aryl Hydrocarbon Receptor Interacting Protein (AIP) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | 0.94 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5FWY5 |
| Gene ID | 282827 |
| NCBI Accession | NP_758830.2, XP_006230761.1, XP_006230762.1 |
| Alias | ARA9,FKBP16,FKBP37,PITA1,SMTPHN,XAP-2 |
| Background | Elisa Kits for: AIP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
The Aryl-hydrocarbon-interacting protein (AIP), also known as aryl hydrocarbon receptor-interacting protein, is a cellular protein that interacts with the aryl hydrocarbon receptor (AhR). AhR is a ligand-activated transcription factor that plays a crucial role in the regulation of gene expression in response to environmental toxins, such as dioxins, polycyclic aromatic hydrocarbons (PAHs), and other xenobiotics. AIP acts as a chaperone protein for AhR, assisting in its proper folding, stabilization, and nuclear translocation upon ligand binding. Through its interaction with AhR, AIP regulates the transcriptional activity of AhR-dependent genes involved in xenobiotic metabolism, detoxification, and other cellular processes. Mutations in the AIP gene are associated with a rare hereditary condition known as familial isolated pituitary adenoma (FIPA). Individuals with FIPA develop benign tumors of the pituitary gland, which can lead to hormonal imbalances and various health issues. These mutations disrupt the normal function of AIP, impairing its ability to interact with AhR and regulate its activity effectively.
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