Rat Apolipoprotein C2 (APOC2) ELISA Kit

Este producto es parte de APOC2 - Apolipoprotein C2
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611€ (96 tests)

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935106861
info@markelab.com
name
Rat Apolipoprotein C2 (APOC2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx575747
tested applications
ELISA

Description

Rat Apolipoprotein C2 (APOC2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Apolipoprotein C2 concentrations in serum, plasma and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Apolipoprotein C2 (APOC2)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
3.12 ng/ml - 200 ng/ml
Sensitivity
1.88 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
G3V8D4
Alias
APOC2, APO-CII, APOC-II, apolipoprotein C2,Apolipoprotein C-II
Background
Elisa kits for APOC2
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

APOC2 is a key component of VLDL and chylomicrons, playing an essential role in triglyceride metabolism as an activator of lipoprotein lipase (LPL). APOC2 is primarily synthesized in the liver and secreted into the plasma, where it facilitates the hydrolysis of triglycerides in chylomicrons and VLDL into free fatty acids and glycerol for energy production or storage. A deficiency or mutation in the APOC2 gene leads to familial chylomicronemia syndrome (FCS), a rare genetic disorder characterized by elevated triglyceride levels, severe hyperlipidemia, and recurrent pancreatitis. APOC2 levels are tightly regulated to maintain lipid balance, as excess or reduced APOC2 activity can disrupt triglyceride clearance and promote atherosclerosis. APOC2 functions cooperatively with other apolipoproteins, such as APOA5 and APOE, to regulate lipid metabolism. Therapeutic strategies targeting APOC2 pathways are being explored to improve triglyceride clearance and reduce cardiovascular risk in individuals with dyslipidemia.

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