Rat Apolipoprotein A4 (APOA4) Protein
247€ (10 µg)
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name
Rat Apolipoprotein A4 (APOA4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168802
tested applications
WB, SDS-PAGE
Description
Rat APOA4 Protein is a recombinant Rat protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Apolipoprotein A4 (APOA4) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Glu21-Ser391 Tag: N-terminal His tag and GST tag |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 72.4 kDa Observed MW (SDS-PAGE): 72 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P02651 |
| Alias | APOA4, apolipoprotein A4, APO A4,APO A-4,apoA-IV,apoAIV,apoA4,Apolipoprotein A-IV |
| Background | Protein APOA4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in ddH2O to a concentration between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
APOA4 is a protein primarily synthesized in the small intestine and secreted into the bloodstream as a component of chylomicrons during dietary fat absorption. It plays a key role in lipid metabolism, facilitating the transport and metabolism of triglycerides and cholesterol. APOA4 has been shown to activate lecithin-cholesterol acyltransferase (LCAT), promoting cholesterol esterification and contributing to reverse cholesterol transport. Additionally, APOA4 exhibits anti-inflammatory and antioxidant properties, protecting against atherosclerosis and cardiovascular diseases. It also regulates satiety by interacting with receptors in the hypothalamus, contributing to appetite control and energy balance. Elevated APOA4 levels are associated with improved lipid profiles, while its deficiency can impair lipid transport and metabolism.
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