Rat Anaphase Promoting Complex Subunit 5 (ANAPC5) ELISA Kit

Este producto es parte de ANAPC - Anaphase-promoting complex subunit
Rat Anaphase Promoting Complex Subunit 5 (ANAPC5) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ANAPC5

proveedor

Abbexa

reference

abx502125

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Anaphase Promoting Complex Subunit 5 (ANAPC5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Anaphase Promoting Complex Subunit 5 (ANAPC5) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

ANAPC5 is a structural subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) that contributes to the stability and assembly of the complex. It interacts with other subunits to form the platform necessary for substrate recognition and ubiquitination. ANAPC5 facilitates the recruitment of co-activators such as CDC20 and CDH1, which are required for targeting specific proteins for proteolysis during the cell cycle. By promoting the degradation of regulators like securin and cyclin B, ANAPC5 ensures proper chromosome segregation and mitotic exit. Loss or mutation of ANAPC5 impairs APC/C function, leading to cell cycle arrest, chromosomal instability, and an increased risk of cancer. ANAPC5’s role in the structural integrity of APC/C highlights its importance in maintaining genomic stability and normal cell division. Dysregulation of ANAPC5 is a hallmark of mitotic errors often observed in tumorigenesis.

Características del producto

category

ELISA Kits


immunogen target

Anaphase Promoting Complex Subunit 5 (ANAPC5)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


size 1

96 tests


alias

ANAPC5,APC5,Cyclosome subunit 5


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ANAPC5


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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