Rat Alpha- And Gamma-Adaptin-Binding Protein P34 (AAGAB) ELISA Kit

Este producto es parte de AAGAB - Alpha and Gamma Adaptin Binding Protein P34
Rat Alpha- And Gamma-Adaptin-Binding Protein P34 (AAGAB) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AAGAB

proveedor

Abbexa

reference

abx390965

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Alpha- And Gamma-Adaptin-Binding Protein P34 (AAGAB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alpha- And Gamma-Adaptin Binding Protein (AAGAB) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Alpha- and Gamma-Adaptin-Binding Protein P34 (AAGAB) is a cytoplasmic protein that interacts with adaptin proteins, which are part of the clathrin-mediated endocytosis machinery. AAGAB plays a crucial role in regulating vesicular trafficking, including the internalization and recycling of cell surface receptors and membrane proteins. It is involved in maintaining cellular homeostasis by mediating the transport of molecules between the plasma membrane, endosomes, and other intracellular compartments. Mutations in the AAGAB gene are linked to palmoplantar keratoderma (PPK), a skin disorder characterized by hyperkeratosis of the palms and soles, due to defective vesicular transport and keratinocyte function. Emerging research suggests that AAGAB may also influence cell signaling and proliferation through its role in membrane protein trafficking. Its importance in cellular dynamics highlights its potential as a target for understanding and treating vesicle transport-related disorders.

Características del producto

category

ELISA Kits


immunogen target

Alpha- And Gamma-Adaptin-Binding Protein P34 (AAGAB)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

p34,PPP1,PPKP1,PPKP1A


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AAGAB


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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