Rat Alpha Adducin (ADD1) ELISA Kit

Este producto es parte de ADD - Adducin ( Alpha,Beta,Gamma)
Rat Alpha Adducin (ADD1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ADD1

proveedor

Abbexa

reference

abx501102

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Alpha Adducin (ADD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alpha-adducin concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ADD1 encodes alpha-adducin, a cytoskeletal protein that plays a key role in the assembly and maintenance of the actin-spectrin network, a critical component of the cell cortex. Alpha-adducin is primarily expressed in the brain and kidneys, where it contributes to cellular processes such as membrane stability, ion transport regulation, and cell signaling. It is particularly important in erythrocytes, where it stabilizes the spectrin-actin lattice to maintain red blood cell shape and flexibility. Genetic variations in ADD1 have been associated with hypertension and cardiovascular diseases due to its role in modulating sodium transport in renal epithelial cells. Additionally, alpha-adducin is involved in neuronal morphology and synaptic plasticity, highlighting its importance in neural development and function. Dysregulation or mutations can lead to cellular structural defects and associated diseases.

Características del producto

category

ELISA Kits


immunogen target

Alpha Adducin (ADD1)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

ADDA,ADDUCIN 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ADD1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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