Rat Alpha Actinin 1 (ACTN1) ELISA Kit

Este producto es parte de ACTN - Actinin Alpha
Rat Alpha Actinin 1 (ACTN1) ELISA Kit
715€ (96 tests)

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Name
Rat Alpha Actinin 1 (ACTN1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx512756
Tested Applications
ELISA

Description

Rat Alpha Actinin 1 (ACTN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alpha Actinin 1 (ACTN1) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Alpha Actinin 1 (ACTN1)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.071 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9Z1P2
Alias
BDPLT15
Background
Elisa Kits for: ACTN1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

ACTN1 encodes alpha-actinin-1, a member of the actin-binding protein family that plays a key role in cytoskeletal organization and cellular architecture. It is primarily expressed in non-muscle cells, where it functions as a crosslinker of actin filaments and regulates the assembly of the actin cytoskeleton. ACTN1 is involved in diverse cellular processes such as cell adhesion, migration, and signaling, contributing to tissue integrity and dynamic cellular responses. It is also implicated in the regulation of focal adhesions and mechanotransduction. Mutations in ACTN1 have been associated with autosomal dominant macrothrombocytopenia, characterized by abnormally large platelets and reduced platelet count, highlighting its role in platelet formation and function. Its interaction with actin filaments and various signaling proteins underscores its importance in maintaining cellular stability and enabling dynamic cellular behaviors.

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