Rat Aldose reductase-related protein 1 (AKR1B7) ELISA Kit

Este producto es parte de AKR1B - Aldo-keto reductase family 1 member B
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Aldose reductase-related protein 1 (AKR1B7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501517
tested applications
ELISA

Description

Rat Aldose reductase-related protein 1 (AKR1B7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aldose reductase-related protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetAldose reductase-related protein 1 (AKR1B7)
ReactivityRat
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ5RJP0
AliasAKR1B10,AKR1B11,AKR1B12,ALDRLn,ARL-1,ARL1
BackgroundElisa kits for AKR1B7
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Aldo-Keto Reductase Family 1 Member B7 (AKR1B7) is an enzyme belonging to the aldo-keto reductase superfamily, which catalyzes the reduction of aldehydes and ketones to their corresponding alcohols. AKR1B7 is primarily expressed in adrenal glands, kidneys, and other steroidogenic tissues, where it plays a significant role in detoxifying reactive aldehydes and regulating lipid and steroid metabolism. It is also involved in the detoxification of lipid peroxidation byproducts, protecting cells from oxidative damage and maintaining cellular redox balance. In addition to its metabolic functions, AKR1B7 has been implicated in the biosynthesis of bile acids and steroid hormones by modulating intermediate metabolite levels. Dysregulation of AKR1B7 has been associated with metabolic disorders and certain cancers, where altered lipid metabolism contributes to disease progression. AKR1B7 is gaining attention as a potential biomarker for oxidative stress and metabolic diseases, and it represents a promising therapeutic target in conditions where lipid peroxidation and redox imbalance play critical roles.

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abx501517

Rat Aldose reductase-related protein 1 (AKR1B7) ELISA Kit

Rat Aldose reductase-related protein 1 (AKR1B7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aldose reductase-related protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.

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