Rat Aldo-Keto Reductase Family 1 Member E2 (AKR1E2) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Aldo-Keto Reductase Family 1 Member E2 (AKR1E2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501429
tested applications
ELISA
Description
Rat Aldo-Keto Reductase Family 1 Member E2 (AKR1E2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat 1,5-anhydro-D-fructose reductase concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Aldo-Keto Reductase Family 1 Member E2 (AKR1E2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5U1Y4 |
| Alias | AKR1E2,AKR1CL2,AKRDC1 |
| Background | Elisa kits for AKR1E2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AKR1E2 is a less characterized member of the aldo-keto reductase superfamily but is known to catalyze the reduction of various aldehydes and ketones, contributing to cellular detoxification and redox balance. AKR1E2 has a broad substrate specificity, metabolizing reactive aldehydes such as those derived from lipid peroxidation (4-HNE) and environmental toxins. Its enzymatic activity protects cells from oxidative stress and damage caused by reactive carbonyl species (RCS), linking it to cellular defense mechanisms. While its tissue-specific expression and physiological roles are still being elucidated, AKR1E2 likely plays a role in liver and kidney detoxification processes. Emerging evidence suggests its involvement in redox regulation and energy metabolism under stress conditions. Dysregulation of AKR1E2 may contribute to oxidative stress-associated diseases, including neurodegeneration, cardiovascular disease, and cancer, where impaired detoxification exacerbates cellular damage. Further studies are needed to clarify its unique functions and therapeutic potential.
