Rat Aldo-keto reductase family 1 member C21 (AKR1C21) ELISA Kit

Este producto es parte de AKR1C- Aldo-keto reductase family 1 member C
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Aldo-keto reductase family 1 member C21 (AKR1C21) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501377
tested applications
ELISA

Description

Rat Aldo-keto reductase family 1 member C21 (AKR1C21) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aldo-keto reductase family 1 member C21 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Aldo-keto reductase family 1 member C21 (AKR1C21)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6AYQ2
Alias
Akr1c21
Background
Elisa Kits for: AKR1C21
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

Aldo-Keto Reductase Family 1 Member C21 (AKR1C21) is part of the AKR family of enzymes that catalyze the reduction of ketones and aldehydes, focusing primarily on steroid hormone metabolism. It is expressed in tissues such as the liver and kidneys and plays a role in the conversion of active steroid hormones into their inactive forms, regulating receptor-mediated hormonal effects. AKR1C21 also detoxifies lipid-derived reactive aldehydes, contributing to cellular protection against oxidative stress. Alterations in AKR1C21 expression or activity have been associated with metabolic disorders, inflammatory diseases, and certain cancers. AKR1C21 is of interest in therapeutic research for its potential to modulate steroid levels and protect against oxidative stress-related pathologies, offering insights into novel treatment strategies for endocrine and metabolic diseases.

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