Rat Aldo-keto reductase family 1 member C18 (AKR1C18) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Aldo-keto reductase family 1 member C18 (AKR1C18) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501424
tested applications
ELISA
Description
Rat Aldo-keto reductase family 1 member C18 (AKR1C18) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aldo-keto reductase family 1 member C18 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Aldo-keto reductase family 1 member C18 (AKR1C18) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P51652 |
| Alias | 20-alpha-hydroxysteroid dehydrogenase (20-alpha-HSD) |
| Background | Elisa kits for AKR1C18 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Aldo-Keto Reductase Family 1 Member C18 (AKR1C18) is a key enzyme in steroid metabolism, contributing to the activation and inactivation of glucocorticoids, androgens, and other ketosteroids. AKR1C18 is expressed in various tissues, including the adrenal gland and liver, where it influences stress responses, inflammation, and metabolic processes. By modulating the levels of active steroid hormones, AKR1C18 plays a crucial role in maintaining hormonal balance and homeostasis. Dysregulation of AKR1C18 activity has been linked to disorders such as metabolic syndrome, inflammation, and hormone-sensitive cancers. It is also involved in detoxifying lipid peroxidation products, highlighting its role in protecting cells from oxidative damage. Studies are exploring its potential as a biomarker and therapeutic target in conditions where steroid and oxidative stress pathways are dysregulated.
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