Rat Aldehyde Dehydrogenase 3 Family Member A1 (ALDH3A1) ELISA Kit

Este producto es parte de ALDH - Aldehyde dehydrogenase family member
Rat Aldehyde Dehydrogenase 3 Family Member A1 (ALDH3A1) ELISA Kit
715€ (96 tests)

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Name
Rat Aldehyde Dehydrogenase 3 Family Member A1 (ALDH3A1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx501489
Tested Applications
ELISA

Description

Rat Aldehyde Dehydrogenase 3 Family Member A1 (ALDH3A1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aldehyde dehydrogenase, dimeric NADP-preferring concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Aldehyde Dehydrogenase 3 Family Member A1 (ALDH3A1)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P11883
Alias
ALDH3A1,ALDH3,ALDHIII
Background
Elisa Kits for: ALDH3A1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

ALDH3A1 is a cytosolic enzyme that metabolizes aldehydes derived from lipid peroxidation, environmental toxins, and chemotherapeutic agents. It is highly expressed in the cornea, where it protects ocular tissues from UV-induced oxidative stress and maintains transparency. ALDH3A1 detoxifies reactive aldehydes such as 4-HNE and malondialdehyde, preventing protein and DNA damage under oxidative conditions. It also contributes to cellular antioxidant defenses by generating NADPH, which supports glutathione regeneration. Overexpression of ALDH3A1 has been observed in various cancers, where it promotes resistance to chemotherapy and radiation by neutralizing toxic aldehydes. ALDH3A1’s ability to regulate cell proliferation and survival makes it a target for cancer therapy, particularly in chemoresistant tumors. In addition, its role in protecting ocular tissues highlights its therapeutic potential for preventing UV-induced eye damage and cataract formation.

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