Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADH5
proveedor
Abbexareference
abx501129Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alcohol dehydrogenase class-3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADH5, also known as formaldehyde dehydrogenase, is ubiquitously expressed and functions primarily in the detoxification of formaldehyde, a toxic metabolic byproduct. It catalyzes the oxidation of formaldehyde to formate, using glutathione as a cofactor, and plays a critical role in cellular defense against formaldehyde-induced toxicity and oxidative stress. ADH5 is less active in ethanol metabolism compared to other ADH enzymes but is crucial for maintaining cellular homeostasis and protecting against DNA and protein damage caused by aldehyde accumulation. Its ubiquitous expression highlights its systemic importance in detoxification pathways. Dysregulation of ADH5 is associated with increased susceptibility to formaldehyde-related toxicities and may contribute to cancer progression in tissues exposed to high levels of formaldehyde. Mutations or polymorphisms in ADH5 can impair detoxification efficiency, exacerbating cellular stress and damage.
Características del producto
category
ELISA Kits
immunogen target
Alcohol Dehydrogenase Class-3 (ADH5)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Adh-5,Adh3,GSNOR
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADH5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Recombinant Human ADH5

proveedor
FineTestreference
P0782Tested Applications
Western Blot, ELISAstatus
RUOPrecio a consultar
Ver másRecombinant Human ADH5

proveedor
FineTestreference
P4706Tested Applications
Western Blot,ELISAstatus
RUOPrecio a consultar
Ver másAlcohol Dehydrogenase Class-3 (ADH5) Antibody

proveedor
Abbexareference
abx001658Tested Applications
ELISA, WB, IF/ICCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalADH5 Antibody is a Rabbit Polyclonal antibody against ADH5. This gene encodes a member of the alcohol dehydrogenase fami...
195€ (20 µl)
Ver más