Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501129
tested applications
ELISA
Description
Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alcohol dehydrogenase class-3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alcohol Dehydrogenase Class-3 (ADH5) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P12711 |
| Alias | Adh-5,Adh3,GSNOR |
| Background | Elisa kits for ADH5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADH5, also known as formaldehyde dehydrogenase, is ubiquitously expressed and functions primarily in the detoxification of formaldehyde, a toxic metabolic byproduct. It catalyzes the oxidation of formaldehyde to formate, using glutathione as a cofactor, and plays a critical role in cellular defense against formaldehyde-induced toxicity and oxidative stress. ADH5 is less active in ethanol metabolism compared to other ADH enzymes but is crucial for maintaining cellular homeostasis and protecting against DNA and protein damage caused by aldehyde accumulation. Its ubiquitous expression highlights its systemic importance in detoxification pathways. Dysregulation of ADH5 is associated with increased susceptibility to formaldehyde-related toxicities and may contribute to cancer progression in tissues exposed to high levels of formaldehyde. Mutations or polymorphisms in ADH5 can impair detoxification efficiency, exacerbating cellular stress and damage.
