Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit

Este producto es parte de ADH - Alcohol dehydrogenase
Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ADH5

proveedor

Abbexa

reference

abx501129

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Alcohol Dehydrogenase Class-3 (ADH5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alcohol dehydrogenase class-3 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ADH5, also known as formaldehyde dehydrogenase, is ubiquitously expressed and functions primarily in the detoxification of formaldehyde, a toxic metabolic byproduct. It catalyzes the oxidation of formaldehyde to formate, using glutathione as a cofactor, and plays a critical role in cellular defense against formaldehyde-induced toxicity and oxidative stress. ADH5 is less active in ethanol metabolism compared to other ADH enzymes but is crucial for maintaining cellular homeostasis and protecting against DNA and protein damage caused by aldehyde accumulation. Its ubiquitous expression highlights its systemic importance in detoxification pathways. Dysregulation of ADH5 is associated with increased susceptibility to formaldehyde-related toxicities and may contribute to cancer progression in tissues exposed to high levels of formaldehyde. Mutations or polymorphisms in ADH5 can impair detoxification efficiency, exacerbating cellular stress and damage.

Características del producto

category

ELISA Kits


immunogen target

Alcohol Dehydrogenase Class-3 (ADH5)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

Adh-5,Adh3,GSNOR


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ADH5


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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Alcohol Dehydrogenase Class-3 (ADH5) Antibody

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reactivity

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status

RUO

clonality

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