Rat Agtr2 (Type-2 angiotensin II receptor) ELISA Kit
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name
Rat Agtr2 (Type-2 angiotensin II receptor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0400
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 78.125-5000pg/ml |
| Sensitivity | 46.875pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P35351 |
| Alias | AGTR2,AT2, ATGR2, MRX88,angiotensin receptor 2,angiotensin II type 2 receptor,AT2 receptor,Agtr2 |
| Background | Elisa kits for Agtr2 |
| Status | RUO |
AGTR2 is a G-protein-coupled receptor (GPCR) that binds angiotensin II, exerting effects that often counterbalance the actions of the angiotensin II receptor type 1 (AGTR1). AGTR2 is expressed in various tissues, including the fetal nervous system, vascular endothelium, kidneys, and heart, and its expression decreases after birth but remains significant in specific contexts, such as injury or disease. Unlike AGTR1, AGTR2 primarily mediates vasodilation, anti-inflammatory effects, antiproliferative actions, and pro-apoptotic signaling, contributing to cardiovascular and tissue protection. AGTR2 signaling involves activation of protein phosphatases, nitric oxide (NO) production, and the modulation of signaling pathways like p38 MAPK and Akt, promoting its protective effects on the vasculature and reducing oxidative stress. Dysregulation of AGTR2 has been linked to vascular remodeling, hypertension, and neurological disorders, including cerebral ischemia and neurodegeneration. Additionally, AGTR2 is implicated in promoting angiogenesis and maintaining neuronal growth during development.
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Rat Agtr2 (Type-2 angiotensin II receptor) ELISA Kit
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