Rat ADP Ribosyltransferase 4 (ART4) Protein
1235€ (100 µg)
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935106861
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name
Rat ADP Ribosyltransferase 4 (ART4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691646
tested applications
SDS-PAGE
Description
Rat ART4 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat ART4 (Met1-Lys269) was expressed with a polyhistidine tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ART4 |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Lys269 Tag: C-terminal His tag |
| Origin | Rat |
| Observed MW | 28.4 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_001166980.1 |
| Alias | ADP-ribosyltransferase C2 and C3 toxin-like 4,Dombrock blood group,DO,DOK1,ARTC4,CD297,DO/ART4,Ecto-ADP-ribosyltransferase 4,Mono(ADP-ribosyl)transferase 4 |
| Background | Protein ART4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
ADP-ribosyltransferase 4 (ART4), also known as CD297, is an enzyme that belongs to the ART family of ADP-ribosyltransferases. These enzymes mediate the transfer of ADP-ribose from NAD+ (nicotinamide adenine dinucleotide) to specific target proteins, a modification that alters their functions. ADP-ribosylation is a post-translational modification that can impact a variety of cellular processes, such as signaling, immune regulation, and cell differentiation. ART4 is a GPI-anchored ectoenzyme, meaning it is attached to the outer surface of the plasma membrane and targets extracellular proteins. ART4 is particularly known for its association with the Dombrock (Do) blood group system, where variations in ART4 contribute to antigenic diversity on red blood cells. Its functions and expression are implicated in immune cell regulation, and it has been investigated for potential roles in immune and hematologic disorders.
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